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Machine learning to design peptides for eye medicines

Maryland and Johns Hopkins will use a $2.35 million grant to develop machine-learning-designed peptides for longer-lasting eye medicines.

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Researchers at the University of Maryland and Johns Hopkins plan to use machine learning to design drug-delivery peptides intended to bind ocular melanin, penetrate eye tissue and remain non-toxic. A new $2.35 million National Eye Institute grant supports preclinical laboratory work on longer-lasting eye medicines.

The project builds on a 2023 study in which a 12-amino-acid peptide extended the eye retention of the glaucoma drug brimonidine from eight days to as long as 18 days. The new project has not produced a clinically tested drop or a treatment that replaces injections.

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    Machine learning to design peptides for eye medicines

    Maryland and Johns Hopkins will use a $2.35 million grant to develop machine-learning-designed peptides for longer-lasting eye medicines.

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The event date follows the source institution’s announcement. Results are limited to the study or institutional report; prospective applications are not presented as completed products or clinical outcomes.

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Announced NEI research grant
2.35 million USD
2026-10-14 · Observed
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These are source-announced grants or study indicators; the date is the report day. Grants are not expenditure; classification and chemistry findings retain the reported experiment/model scope.

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