# Delaware method profiles plant proteins without first extracting cells

> Researchers report a validated method that digests proteins in methanol-fixed plant tissue. They applied it to healthy and fungus-infected tobacco leaves.

- Canonical URL: https://newsverum.com/en/news/delaware-intact-cell-plant-proteomics-method-2026
- Publisher: Newsverum
- Section: Agriculture
- Country: United States
- Published: 2026-10-15T23:48:24+00:00
- Updated: 2026-10-15T23:48:24+00:00
- Source review period: 2026-10-13
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*The source does not state the event date; the period shown is the source review period.*

University of Delaware researchers validated a proteomics method that digests proteins inside methanol-fixed plant tissue instead of grinding tissue and isolating proteins first. The approach preserves pathology information within cells while allowing proteins to be identified and measured.

The team applied it to healthy and fungus-infected tobacco leaves, finding immune-related proteins in plant cell-to-cell communication vesicles and toxic proteins in vesicles from the fungal pathogen. The university says more than 15 campus laboratories have used the platform, which is licensed to a supplier. It may support plant-disease research; it is not a field-validated diagnostic test or treatment.

## Data

### In-tissue proteomics method

Proteins were digested and measured within methanol-fixed plant tissue.

Methodology: The method was demonstrated on healthy and fungus-infected tobacco leaves; the source does not report a field test or treatment.

| date | label | description | status |
|---|---|---|---|
| 2026-10-13 | Method reported | The Delaware team reported a validated plant-cell proteomics method. | occurred |

Sources: <https://www.udel.edu/udaily/2026/october/protein-plant-health-biology/> · Download data: [JSON](https://newsverum.com/api/v1/articles/delaware-intact-cell-plant-proteomics-method-2026/data/plant-proteomics-method-report?lang=en&format=json) · [CSV](https://newsverum.com/api/v1/articles/delaware-intact-cell-plant-proteomics-method-2026/data/plant-proteomics-method-report?lang=en&format=csv)

### Source-reported indicators

Proteins were digested and measured within methanol-fixed plant tissue.

Methodology: Values retain the source basis. Annual feed figures are 2025 sector estimates; the October seed count uses the deposit period. Other dates identify report publication, not experiment day. Laboratory oil-holding capacity is not nutritional fat content; counts do not establish production or scale-up success.

| label | value | unit | period | basis | value_qualifier |
|---|---|---|---|---|---|
| Campus laboratories using the platform: lower bound | 15 | count | 2026-10-13 | observed | lower-bound |

Sources: <https://www.udel.edu/udaily/2026/october/protein-plant-health-biology/> · Download data: [JSON](https://newsverum.com/api/v1/articles/delaware-intact-cell-plant-proteomics-method-2026/data/reported-observations?lang=en&format=json) · [CSV](https://newsverum.com/api/v1/articles/delaware-intact-cell-plant-proteomics-method-2026/data/reported-observations?lang=en&format=csv)

## Sources

- [University of Delaware](<https://www.udel.edu/udaily/2026/october/protein-plant-health-biology/>) (Source checked: 2026-10-15; Published: 2026-10-13)

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